Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086549 | 1.00 | GPR119 (0.48) | GPR119KCNH2CHRM4GRM2GRM3 | |
| SCHEMBL27086477 | 0.81 | GPR119 (0.57) | GPR119KCNH2CHRM4CHRM2CHRM1 | |
| SCHEMBL3425233 | 0.80 | HRH4 (0.42) | GPR119 | |
| Hydrochloric Acid SCHEMBL27086736 | 0.80 | GPR119 (0.56) | GPR119KCNH2CHRM4CHRM2CHRM1 | |
| SCHEMBL24437526 | 0.79 | GPR119 (0.48) | GPR119KCNH2GRM2CHRM2CHRM1 | |
| SCHEMBL3424759 | 0.77 | HRH4 (0.46) | — | |
| SCHEMBL121187 | 0.77 | GPR119 (0.49) | GPR119KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL9085482 | 0.76 | NPC1 (0.38) | GPR119CYP2D6 | |
| SCHEMBL30001428 | 0.75 | GPR119 (0.52) | GPR119KCNH2CHRM2CHRM1CHRM3 | |
| SCHEMBL1296739 | 0.75 | GPR119 (0.49) | GPR119KCNH2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022216709-A1 | GPR119 AGONISTS | KALLYOPE, INC. (US) | 2022-10-13 | — | — | WO | disclosed |