Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20553028 | 1.00 | ADRB2 (0.58) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11235495 | 0.92 | ATM (0.59) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL11239636 | 0.91 | ATM (0.58) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL20553595 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL30001555 | 0.82 | ADRB2 (0.57) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL10740750 | 0.82 | ADRB2 (0.67) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL10738074 | 0.81 | ADRB2 (0.65) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11238941 | 0.80 | ATM (0.56) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11241619 | 0.79 | ATM (0.56) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL8057887 | 0.79 | ATM (0.72) | ADRB2ADRB1HTR1AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | ADRB2 61/4885ADRB1 129/4885HTR1A 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.