Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600816 | 1.00 | CASP6 (0.49) | CASP6GFERMAPTMEN1KMT2A | |
| SCHEMBL30331532 | 0.90 | HDAC1 (0.42) | CASP6GFERMEN1KMT2AHDAC1 | |
| SCHEMBL25140046 | 0.90 | HDAC1 (0.42) | CASP6GFERMEN1KMT2AHDAC1 | |
| SCHEMBL12466602 | 0.88 | MAPT (0.51) | MAPTMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL21600746 | 0.88 | HDAC1 (0.52) | GFERMAPTMEN1KMT2AHDAC1 | |
| SCHEMBL16071545 | 0.87 | HDAC1 (0.51) | GFERMAPTMEN1KMT2AHDAC1 | |
| SCHEMBL28533516 | 0.86 | HDAC1 (0.40) | MAPTMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL30043568 | 0.85 | AAK1 (0.43) | MAPTHDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL23606833 | 0.85 | AAK1 (0.43) | MAPTHDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL16071685 | 0.85 | GAA (0.51) | GFERMAPTMEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | SANOFI (FR) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332687-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | CASP6 2878/4885GFER 2462/4885MAPT 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.