Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 4/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892461 | 1.00 | PDE4D (0.37) | PDE4DPDE4BMEN1NPC1CYP3A4 | |
| SCHEMBL30001980 | 0.97 | GNRHR (0.36) | PDE4DPDE4BCYP2C19GNRHRALDH1A1 | |
| SCHEMBL28892468 | 0.97 | GNRHR (0.36) | PDE4DPDE4BCYP2C19GNRHRALDH1A1 | |
| SCHEMBL30003307 | 0.88 | GNRHR (0.42) | MEN1NPC1CYP3A4CYP2C19RAB9A | |
| SCHEMBL10300131 | 0.88 | GNRHR (0.42) | MEN1NPC1CYP3A4CYP2C19RAB9A | |
| SCHEMBL28892707 | 0.84 | GAA (0.39) | PDE4DPDE4BMEN1CYP3A4CYP2C19 | |
| SCHEMBL30002505 | 0.83 | PDE5A (0.43) | PDE4DPDE4BGNRHRLMNAPDE4A | |
| SCHEMBL28892853 | 0.83 | PDE5A (0.43) | PDE4DPDE4BGNRHRLMNAPDE4A | |
| SCHEMBL28892195 | 0.82 | PDE4B (0.38) | PDE4DPDE4BGNRHRPDE4APDE4C | |
| SCHEMBL30002521 | 0.82 | PDE4B (0.38) | PDE4DPDE4BGNRHRPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |