Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 8/20 | 0.61 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.58 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969606 | 1.00 | MAPK3 (0.61) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL30002376 | 0.90 | MAPK3 (0.59) | MAPK3PTK2MAP4K1JAK2NTRK1 | |
| SCHEMBL24752735 | 0.90 | MAPK3 (0.59) | MAPK3PTK2MAP4K1JAK2NTRK1 | |
| SCHEMBL24752696 | 0.89 | MAP4K1 (0.63) | MAPK3PTK2MAP4K1JAK2NTRK1 | |
| SCHEMBL28969633 | 0.88 | MAP4K1 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL30002296 | 0.88 | MAP4K1 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL28969650 | 0.87 | LRRK2 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL30001806 | 0.87 | LRRK2 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL30002231 | 0.87 | LRRK2 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 | |
| SCHEMBL28969572 | 0.87 | LRRK2 (0.54) | MAPK3PTK2GSK3AGSK3BMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253081-A1 | PHOSPHINE OXIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 希格生科（深圳）有限公司 | 2022-12-08 | — | — | WO | disclosed |