Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 9/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095195 | 1.00 | EPAS1 (0.51) | EPAS1LMNAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL16095196 | 1.00 | EPAS1 (0.51) | EPAS1LMNAUSP2ALDH1A1HSD17B10 | |
| SCHEMBL7085874 | 0.87 | EPAS1 (0.46) | EPAS1LMNAALDH1A1HSD17B10TP53 | |
| SCHEMBL28614372 | 0.78 | EPAS1 (0.54) | EPAS1LMNATP53RXFP1MAPT | |
| SCHEMBL29871021 | 0.78 | EPAS1 (0.54) | EPAS1LMNATP53RXFP1MAPT | |
| SCHEMBL5372372 | 0.78 | EPAS1 (0.48) | EPAS1LMNAALDH1A1TP53EPHX2 | |
| SCHEMBL19728699 | 0.77 | EPAS1 (0.49) | EPAS1LMNAALDH1A1TP53RXFP1 | |
| SCHEMBL14484081 | 0.74 | EPAS1 (0.53) | EPAS1ALDH1A1HSD17B10TP53EPHX2 | |
| SCHEMBL28249865 | 0.73 | POLB (0.49) | EPAS1LMNAALDH1A1HSD17B10TP53 | |
| SCHEMBL11554511 | 0.73 | EPAS1 (0.56) | EPAS1LMNAALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419540-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-08-28 | — | — | EP | disclosed |
| EP-4314012-A1 | IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2023069994-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2022204412-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-09-29 | — | — | WO | disclosed |