SCHEMBL3000252

SCHEMBL3000252

CCC=NNC(=O)c1ccncc1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.57
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 1/20 0.54
MPO P05164 1/20 0.54
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HTT P42858 1/20 0.52
USP2 O75604 1/20 0.51
CYP1A2 P05177 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3000250 1.00 L3MBTL1 (0.57) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL2995788 0.87 GAA (0.70) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL2995787 0.87 GAA (0.70) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL3000116 0.84 POLB (0.58) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL3000114 0.84 POLB (0.58) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL2989529 0.84 ASF1A (0.60) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL2989526 0.84 ASF1A (0.60) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL3001411 0.83 POLB (0.57) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL3001408 0.83 POLB (0.57) L3MBTL1MEN1KMT2AALDH1A1MPO
SCHEMBL24784482 0.83 KDM4E (0.60) L3MBTL1MEN1KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) 2010-07-22 US disclosed
EP-2068873-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS Pharma 2100 (DK) 2009-06-17 EP disclosed
WO-2008031440-A2 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS PHARMA 2100 (DK) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184811-A1 ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS ODC1, OTC, ACACB L3MBTL1 1229/4885MEN1 4193/4885KMT2A 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.