Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116334 | 1.00 | NR1H3 (0.44) | NR1H3KMT2AMEN1SCN2ANR1H2 | |
| SCHEMBL3094283 | 0.86 | KMT2A (0.46) | NR1H3KMT2AMEN1SCN2ANR1H2 | |
| SCHEMBL10300135 | 0.84 | CYP3A4 (0.41) | KMT2AMEN1SCN2ACASP3 | |
| SCHEMBL28957713 | 0.83 | GRM1 (0.44) | NR1H3KMT2AMEN1NR1H2ALDH1A1 | |
| SCHEMBL28957692 | 0.81 | CYP3A4 (0.46) | KMT2AMEN1NR1H2CASP6 | |
| SCHEMBL28957696 | 0.80 | GRM1 (0.46) | NR1H3KMT2AMEN1NR1H2ALDH1A1 | |
| SCHEMBL30273421 | 0.80 | GRM1 (0.46) | NR1H3KMT2AMEN1NR1H2ALDH1A1 | |
| SCHEMBL28892345 | 0.79 | MEN1 (0.40) | NR1H3KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5388798 | 0.79 | PPOX (0.56) | NR1H3KMT2AMEN1SCN2ANR1H2 | |
| SCHEMBL10300139 | 0.79 | NR1H3 (0.48) | NR1H3KMT2AMEN1SCN2ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |