Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892341 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL17609992 | 0.81 | AXL (0.47) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL14099867 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL19709638 | 0.78 | AXL (0.44) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL1638897 | 0.78 | CCNE1 (0.47) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL659725 | 0.78 | AXL (0.44) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL3146829 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL26927627 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL27051751 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTRAB9AAXLGFER | |
| SCHEMBL22993546 | 0.77 | ALDH1A1 (0.55) | SMN1; SMN2MAPTRAB9AAXLGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |