SCHEMBL30002854

SCHEMBL30002854

COc1ccc(-c2oc3cc(OCc4ccccc4)cc(OC)c3c(=O)c2O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.74
PPARG P37231 1/20 0.68
KDM4E B2RXH2 4/20 0.62
CYP3A4 P08684 4/20 0.62
MAPT P10636 3/20 0.62
TP53 P04637 2/20 0.62
CASP1 P29466 2/20 0.62
CASP7 P55210 2/20 0.62
LMNA P02545 2/20 0.62
MAOA P21397 2/20 0.58
CYP1A1 P04798 1/20 0.58
CYP1A2 P05177 1/20 0.58
ABCB1 P08183 1/20 0.58
CYP1B1 Q16678 1/20 0.58
FTO Q9C0B1 1/20 0.58
ADORA3 P0DMS8 2/20 0.56
SLC22A2 O15244 1/20 0.56
SLC22A1 O15245 1/20 0.56
DPP4 P27487 1/20 0.55
XDH P47989 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5792138 1.00 ABCG2 (0.74) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL30002869 0.96 ABCG2 (0.74) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL21275469 0.96 ABCG2 (0.74) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL4264761 0.89 L3MBTL1 (0.65) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL2629300 0.86 ABCG2 (1.00) ABCG2KDM4ECYP3A4MAPTTP53
SCHEMBL12621081 0.85 ABCB1 (0.62) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL38650680 0.85 ABCG2 (0.83) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL28536757 0.85 ABCG2 (0.83) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL21275482 0.84 PPARG (0.68) ABCG2PPARGKDM4ECYP3A4MAPT
SCHEMBL30002790 0.84 PPARG (0.68) ABCG2PPARGKDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4322940-A1 SYNTHETIC ROCAGLATES WITH BROAD-SPECTRUM ANTIVIRAL ACTIVITIES AND USES THEREOF Memorial Sloan-Kettering Cancer Center (US) 2024-02-21 EP disclosed
WO-2022221519-A1 SYNTHETIC ROCAGLATES WITH BROAD-SPECTRUM ANTIVIRAL ACTIVITIES AND USES THEREOF MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2022-10-20 WO disclosed