SCHEMBL30002874

SCHEMBL30002874

CC(C(N)=O)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.53
AKR1C3 P42330 3/20 0.50
AKR1C2 P52895 3/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PSEN1 P49768 1/20 0.49
PSEN2 P49810 1/20 0.49
APH1B Q8WW43 1/20 0.49
NCSTN Q92542 1/20 0.49
APH1A Q96BI3 1/20 0.49
PSENEN Q9NZ42 1/20 0.49
EPHX1 P07099 1/20 0.49
CHRM1 P11229 1/20 0.43
PTGS1 P23219 1/20 0.43
TNF P01375 1/20 0.42
SLC6A3 Q01959 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5673527 1.00 APP (0.53) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL5673531 1.00 APP (0.53) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL5234318 0.84 APP (0.64) APPLMNAPSEN1PSEN2APH1B
SCHEMBL38655195 0.84 APP (0.64) APPLMNAPSEN1PSEN2APH1B
SCHEMBL13235896 0.82 AKR1C3 (0.55) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL1512537 0.82 AKR1C3 (0.69) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL31240209 0.82 AKR1C3 (0.69) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL8559116 0.82 ALDH1A1 (0.51) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL1590709 0.82 AKR1C3 (0.69) APPAKR1C3AKR1C2ALDH1A1LMNA
SCHEMBL11008430 0.82 ALDH1A1 (0.46) ALDH1A1LMNAHTTSMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 CN claimed
CN-222305759-U Toluene recovery device in organic synthesis 内蒙古中高化工有限公司 2025-01-07 CN disclosed
CN-119080630-A Preparation method of propanil 锦州怡嘉科技有限公司 2024-12-06 CN disclosed
CN-119080630-A Preparation method of propanil 锦州怡嘉科技有限公司 2024-12-06 CN disclosed
CN-115181033-B Catalytic synthesis method of propanil 内蒙古莱科作物保护有限公司 2024-03-15 CN disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 CN disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 CN disclosed
CN-113402410-B Method for efficiently preparing 3, 4-dichlorophenyl propionamide 宁夏格瑞精细化工有限公司 2023-04-14 CN disclosed
CN-115181033-A Catalytic synthesis method of propanil 内蒙古莱科作物保护有限公司 2022-10-14 CN disclosed