Sugi Predict

Sugi Predict / Compounds / SCHEMBL30003028

SCHEMBL30003028

SCHEMBL30003028

C[Si](O[Si](O[Si](O[Si](C)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ NR1H2 P55055 1/20 0.31
▸ NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175132 0.98 ESR1 (0.38) ESR1ESR2NR1H2NR1H3
SCHEMBL20143198 0.92 ESR1 (0.32) ESR1ESR2
SCHEMBL17123467 0.91 ESR1 (0.34) ESR1ESR2
SCHEMBL30297012 0.88 ESR1 (0.34) ESR1ESR2NR1H2NR1H3
SCHEMBL28420940 0.86 ESR1 (0.34) ESR1ESR2
SCHEMBL18094258 0.86 ESR1 (0.31) ESR1ESR2
SCHEMBL433139 0.85 ESR1 (0.42) ESR1ESR2NR1H2NR1H3
SCHEMBL251487 0.85 ESR1 (0.33) ESR1ESR2
SCHEMBL16521498 0.83 ESR1 (0.38) ESR1ESR2NR1H2NR1H3
SCHEMBL8992173 0.83 ESR1 (0.38) ESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240247107-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-07-25 — — US disclosed
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 — — EP disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 — — WO disclosed