SCHEMBL8992173

SCHEMBL8992173

C[Si](C)(C)O[Si](O[Si](O[Si](O[Si](C)(C)C)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
AGXT P21549 1/20 0.31
CA4 P22748 1/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521498 1.00 ESR1 (0.38) ESR1ESR2NR1H2NR1H3AGXT
SCHEMBL94228 0.97 ESR1 (0.39) ESR1ESR2NR1H2NR1H3AGXT
SCHEMBL93978 0.89 ESR1 (0.34) ESR1ESR2
SCHEMBL17123467 0.89 ESR1 (0.34) ESR1ESR2
SCHEMBL18179380 0.89 ESR1 (0.34) ESR1ESR2
SCHEMBL12458287 0.89 ESR1 (0.34) ESR1ESR2
SCHEMBL19999251 0.87 ESR1 (0.33) ESR1ESR2
SCHEMBL26427810 0.87 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL30003313 0.87 ESR1 (0.33) ESR1ESR2
SCHEMBL26973343 0.87 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438244-B Crosslinkable organosiloxanes alkane modified reaction resins 瓦克化学股份公司 2024-08-30 CN disclosed
US-20240247107-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-07-25 US disclosed
CN-116438244-A Crosslinkable organosiloxane modified reactive resins 瓦克化学股份公司 2023-07-14 CN disclosed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed