SCHEMBL30003052

SCHEMBL30003052

COc1ccc2c(c1)C(=O)C=C(O)C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA4 P22748 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
LCK P06239 3/20 0.48
PRKACA P17612 1/20 0.47
PRKACG P22612 1/20 0.47
PRKACB P22694 1/20 0.47
GAPDH P04406 1/20 0.44
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
APP P05067 1/20 0.43
SNCA P37840 1/20 0.43
USP8 P40818 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9178172 1.00 PTPN1 (0.49) PTPN1ESR1ESR2CA1CA2
SCHEMBL29406983 0.93 PTPN1 (0.53) PTPN1ESR1ESR2CA1CA2
SCHEMBL4294055 0.93 PTPN1 (0.53) PTPN1ESR1ESR2CA1CA2
SCHEMBL5822222 0.81 IDO1 (0.62) PTPN1ESR1ESR2CA1CA2
SCHEMBL30002619 0.81 ALDH1A1 (0.53) PTPN1ESR1ESR2CA1CA2
SCHEMBL12760759 0.81 ALDH1A1 (0.53) PTPN1ESR1ESR2CA1CA2
SCHEMBL30003084 0.81 IDO1 (0.62) PTPN1ESR1ESR2CA1CA2
SCHEMBL23271902 0.79 PTPN1 (0.49) PTPN1ESR1ESR2CA1CA2
SCHEMBL9628296 0.79 PTPN1 (0.49) PTPN1ESR1ESR2CA1CA2
SCHEMBL30004078 0.79 PTPN1 (0.49) PTPN1ESR1ESR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105894-A Preparation method and application of cryptotanshinone compound 中国人民解放军海军军医大学 2023-11-24 CN disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed