Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995478 | 0.83 | SHBG (0.50) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6526132 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6520191 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6520339 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL19332953 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6524071 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6524219 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6527173 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL9237351 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6525332 | 0.81 | SHBG (0.43) | SHBGEPHX1TP53CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |