SCHEMBL30003459

SCHEMBL30003459

Cc1cc(C(=O)CCc2sc(-c3cc(F)cc(F)c3)nc2C(C)C)ccc1OCCO

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 5/20 0.38
PPARG P37231 4/20 0.38
PPARA Q07869 4/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
MAPT P10636 5/20 0.37
LMNA P02545 2/20 0.37
SCD O00767 2/20 0.36
DCK P27707 2/20 0.36
S1PR3 Q99500 2/20 0.35
S1PR1 P21453 1/20 0.35
TP53 P04637 3/20 0.35
TRPM8 Q7Z2W7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658539 1.00 PPARD (0.38) PPARDPPARGPPARATHRATHRB
SCHEMBL24742580 0.96 THRA (0.38) PPARDPPARGPPARATHRATHRB
SCHEMBL30002943 0.91 PPARD (0.40) PPARDPPARGPPARATHRATHRB
SCHEMBL24658597 0.91 PPARD (0.40) PPARDPPARGPPARATHRATHRB
SCHEMBL1765982 0.90 PPARD (0.45) PPARDPPARGPPARAMAPT
SCHEMBL12732420 0.90 PPARD (0.40) PPARDPPARGPPARAMAPTLMNA
SCHEMBL4754169 0.88 PPARD (0.38) PPARDPPARGPPARAMAPTLMNA
SCHEMBL24742071 0.87 PPARD (0.41) PPARDPPARGPPARAMAPTLMNA
SCHEMBL23870829 0.87 PPARD (0.51) PPARDPPARGPPARAMAPT
SCHEMBL30003494 0.87 PPARD (0.51) PPARDPPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.