SCHEMBL30003536

SCHEMBL30003536

Cc1cc(C(=O)CCc2sc(-c3ccc4ccccc4c3)nc2C(C)C)ccc1OC(C)(C)CO

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 8/20 0.40
PPARG P37231 6/20 0.40
PPARA Q07869 6/20 0.40
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
HDAC1 Q13547 1/20 0.33
MAPT P10636 5/20 0.33
TP53 P04637 4/20 0.33
LMNA P02545 2/20 0.33
THRB P10828 1/20 0.33
ECE1 P42892 1/20 0.33
PTGDR2 Q9Y5Y4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26197175 1.00 PPARD (0.40) PPARDPPARGPPARASMN1; SMN2NPC1
SCHEMBL24743197 0.91 PPARD (0.43) PPARDPPARGPPARAMAPTLMNA
SCHEMBL30003698 0.91 PPARD (0.43) PPARDPPARGPPARAMAPTLMNA
SCHEMBL1765907 0.90 PPARD (0.51) PPARDPPARGPPARA
SCHEMBL12732431 0.90 PPARD (0.44) PPARDPPARGPPARASMN1; SMN2NPC1
SCHEMBL30002969 0.88 PPARD (0.54) PPARDPPARGPPARAMAPT
SCHEMBL24742581 0.88 PPARD (0.54) PPARDPPARGPPARAMAPT
SCHEMBL24742071 0.87 PPARD (0.41) PPARDPPARGPPARAMAPTTP53
SCHEMBL30003974 0.87 PPARD (0.41) PPARDPPARGPPARAMAPTTP53
SCHEMBL24656237 0.87 PPARD (0.39) PPARDPPARGPPARASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARG 71/4885PPARA 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.