SCHEMBL30003698

SCHEMBL30003698

Cc1ccc(-c2nc(C(C)C)c(CCC(=O)c3ccc(OC(C)(C)CO)c(C)c3)s2)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 11/20 0.43
PPARA Q07869 9/20 0.43
PPARG P37231 7/20 0.43
MAPT P10636 5/20 0.36
LMNA P02545 1/20 0.36
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
CTNNB1 P35222 1/20 0.34
WNT3A P56704 1/20 0.34
FFAR1 O14842 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24743197 1.00 PPARD (0.43) PPARDPPARAPPARGMAPTLMNA
SCHEMBL12732397 0.92 PPARD (0.45) PPARDPPARAPPARGMAPTLMNA
SCHEMBL30002969 0.92 PPARD (0.54) PPARDPPARAPPARGMAPT
SCHEMBL24742581 0.92 PPARD (0.54) PPARDPPARAPPARGMAPT
SCHEMBL24742071 0.91 PPARD (0.41) PPARDPPARAPPARGMAPTLMNA
SCHEMBL30003974 0.91 PPARD (0.41) PPARDPPARAPPARGMAPTLMNA
SCHEMBL24658598 0.91 PPARD (0.42) PPARDPPARAPPARGMAPTLMNA
SCHEMBL30003422 0.91 PPARD (0.41) PPARDPPARAPPARGMAPTS1PR1
SCHEMBL24656239 0.91 PPARD (0.41) PPARDPPARAPPARGMAPTS1PR1
SCHEMBL30003536 0.91 PPARD (0.40) PPARDPPARAPPARGMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARD 332/4885PPARA 94/4885PPARG 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.