Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991947 | 0.89 | CA1 (0.39) | CYP1A2CYP2D6 | |
| SCHEMBL10766757 | 0.88 | CYP1A2 (0.38) | CYP1A2DPP4CYP2D6 | |
| SCHEMBL20972363 | 0.85 | CYP1A2 (0.45) | CYP1A2DPP4CYP2D6NOS1NOS2 | |
| SCHEMBL28339122 | 0.81 | CYP1A2 (0.50) | CYP1A2DPP4CYP2D6NOS1NOS2 | |
| SCHEMBL10775423 | 0.81 | CYP1A2 (0.33) | CYP1A2CYP2D6 | |
| SCHEMBL11704794 | 0.79 | CYP1A2 (0.39) | CYP1A2DPP4CYP2D6NOS1NOS2 | |
| SCHEMBL19432339 | 0.79 | CYP1A2 (0.39) | CYP1A2DPP4CYP2D6NOS1NOS2 | |
| SCHEMBL28495821 | 0.78 | CHRNB2 (0.41) | CYP1A2DPP4CYP2D6 | |
| SCHEMBL2688034 | 0.77 | CYP1A2 (0.45) | CYP1A2DPP4CYP2D6NOS1NOS2 | |
| SCHEMBL6325157 | 0.75 | CYP1A2 (0.44) | CYP1A2DPP4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |