SCHEMBL30003605

SCHEMBL30003605

Cc1cc2c(CCc3nc(-c4ccc(Cl)cc4Cl)oc3C(C)C)noc2cc1OCCO

nearest known ligand 0.79

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.79
PPARD Q03181 9/20 0.79
PPARG P37231 9/20 0.79
KMO O15229 8/20 0.38
TDP1 Q9NUW8 1/20 0.33
TRPV1 Q8NER1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658289 1.00 PPARA (0.79) PPARAPPARDPPARGKMOTDP1
SCHEMBL1765990 0.89 PPARA (1.00) PPARAPPARDPPARGKMO
SCHEMBL4032210 0.85 PPARG (0.72) PPARAPPARDPPARGKMO
SCHEMBL4025444 0.83 PPARG (0.69) PPARAPPARDPPARGKMO
SCHEMBL12732455 0.82 PPARG (0.88) PPARAPPARDPPARGKMO
SCHEMBL26197203 0.81 PPARA (0.53) PPARAPPARDPPARGTDP1TRPV1
SCHEMBL24658332 0.80 PPARA (0.53) PPARAPPARDPPARGTDP1
SCHEMBL4025100 0.80 PPARG (0.70) PPARAPPARDPPARG
SCHEMBL1765983 0.80 PPARG (0.65) PPARAPPARDPPARGTDP1
SCHEMBL4032718 0.80 PPARG (0.69) PPARAPPARDPPARGKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A PPARA 94/4885PPARD 332/4885PPARG 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.