Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.69 |
| ▸ | PPARA | Q07869 | 9/20 | 0.69 |
| ▸ | PPARD | Q03181 | 8/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026750 | 0.86 | PPARG (0.67) | PPARGPPARAPPARDLMNAHSD17B10 | |
| SCHEMBL4032210 | 0.85 | PPARG (0.72) | PPARGPPARAPPARDHSD17B10KMO | |
| SCHEMBL4025444 | 0.83 | PPARG (0.69) | PPARGPPARAPPARDSMN1; SMN2KMO | |
| SCHEMBL1765990 | 0.82 | PPARA (1.00) | PPARGPPARAPPARDKMO | |
| SCHEMBL1765983 | 0.80 | PPARG (0.65) | PPARGPPARAPPARDLMNATHRB | |
| SCHEMBL4025100 | 0.80 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL24658289 | 0.80 | PPARA (0.79) | PPARGPPARAPPARDKMO | |
| SCHEMBL30003605 | 0.80 | PPARA (0.79) | PPARGPPARAPPARDKMO | |
| SCHEMBL4031117 | 0.78 | PPARG (0.66) | PPARGPPARAPPARDHSD17B10KDM4E | |
| SCHEMBL12732455 | 0.75 | PPARG (0.88) | PPARGPPARAPPARDKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445258-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO (JP) | 2009-06-24 | — | — | EP | disclosed |
| US-7402597-B2 | Activator of peroxisome proliferator-activated receptor δ | NIPPON CHEMIPHAR CO., LTD (JP) | 2008-07-22 | — | — | US | disclosed |
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | SAKUMA SHOGO | 2007-02-01 | — | — | US | disclosed |
| US-7119104-B2 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR, CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1445258-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027196-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | PPARG 2/4885PPARA 1/4885PPARD 3/4885 |
| US-20050096363-A1 | Activator of peroxisome proliferator-activated receptor delta | PPARA, PPARG, PPARD | PPARG 2/4885PPARA 1/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.