SCHEMBL30003631

SCHEMBL30003631

Cc1cc(C(=O)CCc2sc3cc(C(F)(F)F)ccc3c2C(C)C)ccc1CCCO

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.34
LDHB P07195 1/20 0.34
PPARD Q03181 4/20 0.33
PPARG P37231 3/20 0.33
PPARA Q07869 3/20 0.33
DAO P14920 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24743202 1.00 LDHA (0.34) LDHALDHBPPARDPPARGPPARA
SCHEMBL1033622 0.90 PPARD (0.42) LDHALDHBPPARDPPARGPPARA
SCHEMBL1031012 0.88 PPARD (0.35) LDHALDHBPPARDPPARGPPARA
SCHEMBL1035053 0.86 BCL2L1 (0.35) LDHALDHBHSD11B1
SCHEMBL30003789 0.82 DAO (0.32) LDHALDHBDAO
SCHEMBL24742599 0.82 DAO (0.32) LDHALDHBDAO
SCHEMBL1035016 0.81 PPARD (0.41) LDHALDHBPPARDPPARGPPARA
SCHEMBL1031604 0.81 PPARD (0.45) PPARDPPARGPPARA
SCHEMBL1033215 0.80 PPARD (0.40) LDHALDHBPPARDPPARGPPARA
SCHEMBL27988156 0.80 PTGDR2 (0.34) LDHALDHBPPARDPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333379-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2025-10-30 US disclosed
US-12297168-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2025-05-13 US disclosed
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES ABIONYX PHARMA SA (FR) 2024-06-20 US disclosed
US-20230278952-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2023-09-07 US disclosed
US-11634387-B2 Compounds useful for treating liver diseases ABIONYX PHARMA SA (FR) 2023-04-25 US disclosed
US-20220363632-A1 Compounds Useful for Treating Liver Diseases ABIONYX PHARMA SA (FR) 2022-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278952-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885
US-20240199575-A1 COMPOUNDS USEFUL FOR TREATING LIVER DISEASES SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885
US-11634387-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885
US-20250333379-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885
US-12297168-B2 Compounds useful for treating liver diseases SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885
US-20220363632-A1 Compounds Useful for Treating Liver Diseases SLC10A1, FABP1, CPT1A LDHA 510/4885LDHB 679/4885PPARD 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.