Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799941 | 0.80 | EPHX1 (0.63) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL2683478 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL30640703 | 0.77 | EPHX1 (1.00) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL1092135 | 0.75 | EPHX1 (0.73) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL2096781 | 0.75 | EPHX1 (0.73) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL9835107 | 0.75 | EPHX1 (0.73) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL7980935 | 0.75 | NPC1 (0.59) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL14341919 | 0.74 | EPHX1 (0.59) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL733725 | 0.74 | EPHX1 (0.59) | EPHX1EPHX2CA2CA4CA5A | |
| SCHEMBL733724 | 0.74 | EPHX1 (0.59) | EPHX1EPHX2CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218226-A1 | ENGINEERED IMMUNE CELL AND USE THEREOF | 南京北恒生物科技有限公司 | 2022-10-20 | — | — | WO | disclosed |