Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75884 | 0.79 | SMN1; SMN2 (0.54) | NPC1RAB9AEPHX1EPHX2MEN1 | |
| SCHEMBL9799941 | 0.76 | EPHX1 (0.63) | NPC1RAB9AEPHX1EPHX2CA2 | |
| SCHEMBL7980937 | 0.76 | EPHX1 (0.81) | NPC1RAB9AEPHX1EPHX2CA2 | |
| SCHEMBL1092135 | 0.75 | EPHX1 (0.73) | NPC1RAB9AEPHX1EPHX2CA2 | |
| SCHEMBL4254257 | 0.75 | NPC1 (1.00) | NPC1RAB9AEPHX1EPHX2MEN1 | |
| SCHEMBL30003961 | 0.75 | EPHX1 (0.61) | NPC1RAB9AEPHX1EPHX2CA2 | |
| SCHEMBL30369807 | 0.75 | NPC1 (1.00) | NPC1RAB9AEPHX1EPHX2MEN1 | |
| Fluoride SCHEMBL11787935 | 0.73 | EPHX1 (0.70) | NPC1RAB9AEPHX1EPHX2CA2 | |
| Hydrochloric Acid SCHEMBL11153269 | 0.73 | EPHX1 (0.70) | NPC1RAB9AEPHX1EPHX2CA2 | |
| SCHEMBL2683478 | 0.73 | EPHX1 (1.00) | NPC1RAB9AEPHX1EPHX2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |