Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619444 | 1.00 | PDK2 (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL18880905 | 1.00 | PDK2 (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL19013527 | 1.00 | PDK2 (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL25629567 | 0.92 | PDK2 (0.51) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL30501024 | 0.91 | ELANE (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL21364084 | 0.91 | ELANE (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL29056146 | 0.91 | ELANE (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL12619538 | 0.91 | ELANE (0.58) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL24254783 | 0.89 | SMN1; SMN2 (0.50) | PDK2ELANEESR1ESR2LMNA | |
| SCHEMBL19001663 | 0.89 | PDK2 (0.53) | PDK2ELANEESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790629-B | Application of chiral spirofluorene isomer in electronic component with chiral correlation function | 南京工业大学 | 2022-10-14 | — | — | CN | disclosed |