Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29325214 | 1.00 | GID4 (0.41) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL7919900 | 1.00 | GID4 (0.41) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL29325486 | 1.00 | GID4 (0.41) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL13974016 | 0.95 | KMT2A (0.44) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL17180996 | 0.95 | KMT2A (0.44) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL13616719 | 0.95 | KMT2A (0.44) | GID4KMT2AUGT2B17BRD3DRD2 | |
| SCHEMBL29907033 | 0.87 | GID4 (0.45) | GID4KMT2ADRD2DRD1DRD4 | |
| SCHEMBL1868958 | 0.87 | GID4 (0.45) | GID4KMT2ADRD2DRD1DRD4 | |
| SCHEMBL1508638 | 0.87 | GID4 (0.45) | GID4KMT2ADRD2DRD1DRD4 | |
| SCHEMBL29625410 | 0.87 | GID4 (0.45) | GID4KMT2ADRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022218311-A1 | MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF | APPICINE THERAPEUTICS (HK) LIMITED (CN) | 2022-10-20 | — | — | WO | disclosed |