Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | USP5 | P45974 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16912992 | 0.84 | MEN1 (0.61) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL14095893 | 0.84 | MEN1 (0.61) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL78283 | 0.83 | USP2 (0.69) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL655768 | 0.83 | USP2 (0.76) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL11306227 | 0.83 | PKM (0.69) | MEN1KMT2AUSP2PKMHTT | |
| SCHEMBL1019079 | 0.83 | MEN1 (0.60) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL16913002 | 0.83 | MEN1 (0.60) | MEN1KMT2ATDP1USP2PKM | |
| SCHEMBL4212319 | 0.83 | MEN1 (0.75) | MEN1KMT2ATDP1MCOLN3LMNA | |
| SCHEMBL165129 | 0.82 | USP2 (0.80) | MEN1KMT2AUSP2PKMLMNA | |
| SCHEMBL3690418 | 0.82 | USP2 (0.80) | MEN1KMT2AUSP2PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |