Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005938 | 0.89 | ALDH1A1 (0.84) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30006674 | 0.88 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005796 | 0.87 | ALDH1A1 (0.84) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30006634 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005594 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005592 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30006519 | 0.85 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005968 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005473 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL30005360 | 0.82 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |