Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.60 |
| ▸ | ATR | Q13535 | 15/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18454803 | 0.79 | CYP4F2 (0.51) | CYP4F2CYP4A11ATRIDH1 | |
| SCHEMBL20153769 | 0.79 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| SCHEMBL12092426 | 0.77 | CYP4F2 (0.52) | CYP4F2CYP4A11ATR | |
| SCHEMBL25257638 | 0.76 | CYP4F2 (0.53) | CYP4F2CYP4A11ATRIDH1 | |
| SCHEMBL30509486 | 0.76 | CYP4F2 (0.58) | CYP4F2CYP4A11ATR | |
| SCHEMBL9977805 | 0.76 | CYP4F2 (0.58) | CYP4F2CYP4A11ATR | |
| SCHEMBL1814288 | 0.76 | CYP4F2 (0.55) | CYP4F2CYP4A11ATRIDH1 | |
| SCHEMBL20662128 | 0.75 | CYP4F2 (0.54) | CYP4F2CYP4A11ATRIDH1 | |
| SCHEMBL22968022 | 0.75 | CYP4F2 (1.00) | CYP4F2CYP4A11ATR | |
| SCHEMBL18985877 | 0.74 | CYP4F2 (0.50) | CYP4F2CYP4A11ATRIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323062-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | Novartis AG (CH) | 2024-02-21 | — | — | EP | claimed |
| WO-2022219546-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2022-10-20 | — | — | WO | claimed |