Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PARL | Q9H300 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16912986 | 0.86 | SMN1; SMN2 (0.64) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL21681941 | 0.85 | ALDH1A1 (0.74) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL7485956 | 0.85 | ALDH1A1 (0.79) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL1519692 | 0.85 | ALDH1A1 (0.69) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL14055643 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL16912996 | 0.84 | EPHX2 (0.63) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL854322 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2HTTRECQLLMNAALDH1A1 | |
| SCHEMBL3691866 | 0.83 | ALDH1A1 (0.82) | SMN1; SMN2HTTLMNAALDH1A1EPHX2 | |
| SCHEMBL1269605 | 0.83 | ALDH1A1 (0.82) | SMN1; SMN2HTTLMNAALDH1A1EPHX2 | |
| SCHEMBL7130169 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2HTTRECQLLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |