Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30006455 | 0.94 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30005764 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30005504 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30005451 | 0.90 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30004817 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| Trifluoroacetic Acid SCHEMBL30005909 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| Trifluoroacetic Acid SCHEMBL30005732 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30004731 | 0.89 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1NPSR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL30006476 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30006039 | 0.88 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1NPSR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |