SCHEMBL30005359

SCHEMBL30005359

Nc1cc2cc(Br)ccc2c(Br)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.47
MAPT P10636 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PDPK1 O15530 2/20 0.41
JAK2 O60674 2/20 0.41
HTT P42858 1/20 0.38
PLAU P00749 1/20 0.38
PABPC1 P11940 2/20 0.37
RAB9A P51151 2/20 0.37
NPC1 O15118 1/20 0.37
CYP2A6 P11509 1/20 0.37
ACHE P22303 2/20 0.37
HRH4 Q9H3N8 1/20 0.36
CCNB2 O95067 1/20 0.36
CDK1 P06493 1/20 0.36
CCNB1 P14635 1/20 0.36
PRKACA P17612 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1520112 1.00 BACE1 (0.47) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL20079527 0.82 BACE1 (0.46) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL9921934 0.80 BACE1 (0.32) BACE1MAPTKDM4E
SCHEMBL19546876 0.80 BACE1 (0.44) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL28186662 0.80 LMNA (0.44) BACE1MEN1KMT2AALDH1A1KDM4E
SCHEMBL23741461 0.80 APP (0.33) BACE1MAPTKDM4ENOS1
SCHEMBL23048737 0.80 BACE1 (0.44) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL15676507 0.78 CYP2A6 (0.39) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL303815 0.77 KDM4E (0.44) BACE1MAPTMEN1KMT2AALDH1A1
SCHEMBL30064841 0.77 KDM4E (0.44) BACE1MAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120759010-B Preparation method of deodorizing negative ion graphene quantum dot cloud velvet 江苏海科纤维有限公司 2025-12-09 CN disclosed
CN-120759010-A Preparation method of deodorizing negative ion graphene quantum dot cloud velvet 江苏海科纤维有限公司 2025-10-10 CN disclosed
US-11673881-B2 Isoquinolin-3-yl carboxamides and preparation and use thereof BIOSPLICE THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
CN-109311819-B Isoquinolin-3-yl carboxamides, their preparation and their use 萨穆梅德有限公司 2022-10-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11673881-B2 Isoquinolin-3-yl carboxamides and preparation and use thereof DYRK1A, DYRK3, DYRK1B BACE1 1111/4885MAPT 577/4885MEN1 4483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.