Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004863 | 0.93 | ALDH1A1 (0.61) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005449 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005912 | 0.86 | ALDH1A1 (0.79) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005339 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005959 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005950 | 0.84 | ALDH1A1 (0.69) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30006458 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005830 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30005465 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 | |
| SCHEMBL30006662 | 0.80 | ALDH1A1 (0.72) | ALDH1A1KMT2ANPSR1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |