Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | IL1RN | P18510 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34841 | 1.00 | MAPT (0.76) | MAPTIL1RNTSHRRECQLAPEX1 | |
| SCHEMBL28283475 | 0.90 | TSHR (0.77) | TSHRRECQLMAPK1NPC1GAA | |
| SCHEMBL15773014 | 0.87 | TSHR (0.73) | TSHRRECQLMAPK1NPC1GAA | |
| SCHEMBL7321050 | 0.87 | KMT2A (0.80) | MAPTTSHRRECQLMAPK1ALDH1A1 | |
| SCHEMBL2850336 | 0.87 | GAA (0.74) | TSHRRECQLMAPK1NPC1GAA | |
| SCHEMBL3932198 | 0.86 | MAPT (0.94) | MAPTIL1RNTSHRAPEX1NPC1 | |
| SCHEMBL29463849 | 0.86 | MAPT (1.00) | MAPTIL1RNTSHRAPEX1NPC1 | |
| SCHEMBL1001486 | 0.86 | MAPT (1.00) | MAPTIL1RNTSHRAPEX1NPC1 | |
| SCHEMBL1001537 | 0.85 | MAPT (0.97) | MAPTIL1RNTSHRAPEX1NPC1 | |
| SCHEMBL30213397 | 0.85 | MAPT (0.97) | MAPTIL1RNTSHRAPEX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240418723-A1 | SEQUENTIAL TREATMENTS AND BIOMARKERS TO REVERSE RESISTANCE TO KINASE INHIBITORS | QUEEN MARY UNIVERSITY OF LONDON (GB) | 2024-12-19 | — | — | US | disclosed |
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |