Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005630 | 0.93 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30006667 | 0.92 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30006448 | 0.91 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005770 | 0.90 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005546 | 0.90 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005010 | 0.90 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005717 | 0.89 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005394 | 0.89 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005032 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL30005912 | 0.87 | ALDH1A1 (0.79) | ALDH1A1KMT2AMEN1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |