Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 6/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.48 |
| ▸ | ATR | Q13535 | 11/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123495 | 1.00 | CYP4F2 (0.48) | CYP4F2CYP4A11ATREGLN2BTK | |
| SCHEMBL30731682 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| SCHEMBL30731706 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11ATREGLN2 | |
| SCHEMBL27171442 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11ATREGLN2 | |
| SCHEMBL29123471 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| SCHEMBL30005364 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11ATR | |
| SCHEMBL24664798 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11ATRBTK | |
| SCHEMBL30006336 | 0.77 | LTA4H (0.46) | CYP4F2CYP4A11 | |
| SCHEMBL30006051 | 0.77 | CYP4F2 (0.54) | CYP4F2CYP4A11ATRBTK | |
| SCHEMBL24665471 | 0.77 | CYP4F2 (0.54) | CYP4F2CYP4A11ATRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323062-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | Novartis AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2022219546-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2022-10-20 | — | — | WO | disclosed |