Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 3/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586766 | 1.00 | HCRTR1 (0.50) | HCRTR1HCRTR2ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL17028392 | 0.85 | NOTUM (0.41) | HCRTR1HCRTR2ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL302446 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2ALDH1A1KDM4ENOTUM | |
| SCHEMBL17422568 | 0.85 | HCRTR1 (0.46) | HCRTR1HCRTR2ALDH1A1ALOX15NOTUM | |
| SCHEMBL15558561 | 0.84 | NOTUM (0.44) | HCRTR1HCRTR2ALDH1A1ALOX15POLB | |
| SCHEMBL6429865 | 0.83 | NPC1 (0.55) | HCRTR1ALDH1A1TDP1KDM4EMEN1 | |
| SCHEMBL7461975 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2ALDH1A1NOTUM | |
| Hydrochloric Acid SCHEMBL15559329 | 0.82 | NOTUM (0.43) | HCRTR1HCRTR2ALDH1A1ALOX15POLB | |
| SCHEMBL7468796 | 0.81 | MYC (0.53) | HCRTR1HCRTR2ALDH1A1L3MBTL1POLB | |
| SCHEMBL21802451 | 0.81 | ALDH1A1 (0.58) | HCRTR1HCRTR2ALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |