Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21624376 | 1.00 | HSD11B1 (0.32) | HSD11B1ALDH1A1MAPK1SMN1; SMN2AVPR2 | |
| SCHEMBL23648101 | 0.90 | HSD11B1 (0.32) | HSD11B1ALDH1A1MAPK1SMN1; SMN2AVPR2 | |
| SCHEMBL21624333 | 0.85 | PDE7A (0.33) | ALDH1A1SMN1; SMN2AVPR2AVPR1A | |
| SCHEMBL30006774 | 0.84 | — | — | |
| SCHEMBL21624388 | 0.84 | — | — | |
| SCHEMBL21624324 | 0.84 | — | — | |
| SCHEMBL21624364 | 0.82 | AVPR1A (0.36) | ALDH1A1AVPR1A | |
| SCHEMBL23658652 | 0.82 | AVPR2 (0.32) | MAPK1SMN1; SMN2AVPR2AVPR1A | |
| SCHEMBL21624404 | 0.82 | — | — | |
| SCHEMBL21624374 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | claimed |
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |