Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 20/20 | 0.36 |
| ▸ | MDM4 | O15151 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005686 | 0.91 | MDM2 (0.40) | MDM2MDM4TP53 | |
| SCHEMBL30006422 | 0.88 | RBP4 (0.35) | MDM2MDM4TP53 | |
| SCHEMBL30968778 | 0.88 | MDM2 (0.40) | MDM2MDM4TP53 | |
| SCHEMBL30005751 | 0.87 | MDM2 (0.44) | MDM2MDM4TP53 | |
| SCHEMBL30006600 | 0.87 | MDM2 (0.41) | MDM2MDM4TP53 | |
| SCHEMBL30006486 | 0.85 | MDM2 (0.37) | MDM2MDM4TP53 | |
| SCHEMBL30006781 | 0.84 | MDM2 (0.39) | MDM2MDM4TP53 | |
| SCHEMBL30006755 | 0.84 | MDM2 (0.40) | MDM2MDM4TP53 | |
| SCHEMBL30968811 | 0.82 | MDM2 (0.41) | MDM2MDM4TP53 | |
| SCHEMBL30005629 | 0.81 | MDM2 (0.37) | MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120416-A | Small molecule compound with substituted phenyl spiro [ indoline-3, 3' -pyrrolidine ] structure | 中国科学院上海药物研究所 | 2023-11-24 | — | — | CN | disclosed |
| CN-115215872-A | Small molecule compound with substituted phenyl spiro [ indoline-3, 3' -pyrrolidine ] structure | 中国科学院上海药物研究所 | 2022-10-21 | — | — | CN | disclosed |