Dimethyl Succinate

Dimethyl Succinate

SCHEMBL300065

CC1(C)CC(O)CC(C)(C)N1CCO.COC(=O)CCC(=O)OC

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 3/20 0.33
APAF1 O14727 1/20 0.33
CASP6 P55212 1/20 0.33
PPP1CA P62136 1/20 0.33
LMNA P02545 2/20 0.33
EZH2 Q15910 1/20 0.32
EPHX2 P34913 5/20 0.32
EPHX1 P07099 2/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27499875 0.94 TSHR (0.38) TSHRSMN1; SMN2KDM4EAPAF1CASP6
Dimethyl Succinate SCHEMBL28072491 0.88 KDM4E (0.32) TSHRSMN1; SMN2KDM4EAPAF1CASP6
Dimethyl Succinate SCHEMBL4550553 0.87 TSHR (0.43) TSHRSMN1; SMN2KDM4ELMNAEPHX2
SCHEMBL410735 0.85 TSHR (0.38) TSHRSMN1; SMN2KDM4EAPAF1LMNA
Succinic Acid Diethyl Ester SCHEMBL250757 0.85 TSHR (0.37) TSHRLMNAEPHX2ALDH1A1KMT2A
SCHEMBL39066 0.83 KMT2A (0.33) KMT2AL3MBTL1
Succinic Acid SCHEMBL2719778 0.82 APEX1 (0.31) KDM4ELMNA
SCHEMBL210915 0.81 SMN1; SMN2 (0.36) TSHRSMN1; SMN2EZH2ALDH1A1HTT
SCHEMBL8606220 0.80 LMNA (0.34) TSHRSMN1; SMN2LMNAEPHX2ALDH1A1
Alcohol SCHEMBL20676748 0.79 KMT2A (0.35) EZH2KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4225503-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2023-08-16 EP claimed
WO-2022073742-A1 GRINDING AID FOR TITANIUM DIOXIDE PARTICLES KRONOS INTERNATIONAL, INC. (DE) 2022-04-14 WO claimed
US-20220106488-A1 Grinding Aid for Titanium Dioxide Particles KRONOS INTERNATIONAL INC. (DE) 2022-04-07 US claimed
EP-3854484-A2 GRINDING AID FOR GRINDING TITANIUM DIOXIDE Kronos International, Inc. (DE) 2021-07-28 EP claimed
US-20150045485-A1 POLYETHYLENE-BASED RESIN COMPOSITION FOR CONTAINER LID, AND CONTAINER LID JAPAN POLYETHYLENE CORPORATION (JP) 2015-02-12 US claimed
CN-101586017-B Storage light-emitting silicone sealant SANVO ZHONGSHAN AEROSOL CO LTD 2013-07-10 CN claimed
US-7625501-B2 Color-converting photoluminescent film IFIRE IP CORPORATION (CA) 2009-12-01 US claimed
CN-101586017-A Storage light-emitting silicone sealant GUANGDONG SANHE CHEMICAL INDUS (CN) 2009-11-25 CN claimed
EP-1298164-B1 Polyamide resin composition having excellent weather resistance UBE INDUSTRIES (JP) 2006-05-10 EP claimed
WO-2005111171-A1 IMPROVED COLOR-CONVERTING PHOTOLUMINESCENT FILM IFIRE TECHNOLOGY CORP. (CA) 2005-11-24 WO claimed
US-6878762-B2 Polyamide resin composition having excellent weather resistance UBE INDUSTRIES, LTD. (JP) 2005-04-12 US claimed
CN-1408770-A Poly amide resincomposition with good weather resistance UBE INDUSTRIES (JP) 2003-04-09 CN claimed
US-20030065065-A1 Polyamide resin composition having excellent weather resistance UBE INDUSTRIES, LTD. (JP) 2003-04-03 US claimed
EP-1298164-A1 Polyamide resin composition having excellent weather resistance Ube Industries, Ltd. (JP) 2003-04-02 EP claimed
US-5502093-A WEATHERPROOF COMPOSITIONS WITH ENVIRONMENTAL RESISTANCE FOR DISCOLORATION INHIBITION POLYPLASTICS CO., LTD. (JP) 1996-03-26 US claimed
EP-0558280-A1 Chemically amplified resist JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-09-01 EP claimed
EP-0523957-A1 Radiation-sensitive composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-01-20 EP claimed
US-5171770-A Includes benzotriazle derivtives, hindered amines and compound containing at least one tertiary nitrogen atom and at least one metal carboxylate group POLYPLASTICS CO., LTD. (JP) 1992-12-15 US claimed
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US claimed
EP-0171941-B1 WEATHER RESISTANT POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 1990-03-21 EP claimed