Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360066 | 0.86 | TRPV1 (0.55) | TRPV1CCR4 | |
| SCHEMBL31511744 | 0.86 | TRPV1 (0.55) | TRPV1CCR4 | |
| SCHEMBL11949096 | 0.85 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL29334882 | 0.84 | TRPV1 (0.50) | TRPV1CCR4 | |
| SCHEMBL31320721 | 0.82 | TRPV1 (0.55) | TRPV1MEN1KMT2A | |
| SCHEMBL20423769 | 0.81 | TRPV1 (0.48) | TRPV1MEN1KMT2A | |
| SCHEMBL20424005 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2A | |
| SCHEMBL617561 | 0.79 | TRPV1 (0.52) | TRPV1CCR4MEN1KMT2AKDR | |
| SCHEMBL29318661 | 0.79 | CCR4 (0.41) | TRPV1CCR4MEN1KMT2AKDR | |
| SCHEMBL8312915 | 0.78 | CCR4 (0.55) | TRPV1CCR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337642-A1 | ETHACRYNIC ACID DERIVATIVES AS INHIBITORS OF MPRO PROTEASE AND SARS-COV-2 REPLICATION | Universite Euro-Mediterraneenne de Fes (MA) | 2024-03-20 | — | — | EP | claimed |
| WO-2022240277-A1 | ETHACRYNIC ACID DERIVATIVES AS INHIBITORS OF MPRO PROTEASE AND SARS-COV-2 REPLICATION | UNIVERSITE EURO-MEDITERRANEENNE DE FES (MA) | 2022-11-17 | — | — | WO | claimed |
| EP-4337642-A1 | ETHACRYNIC ACID DERIVATIVES AS INHIBITORS OF MPRO PROTEASE AND SARS-COV-2 REPLICATION | Universite Euro-Mediterraneenne de Fes (MA) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240277-A1 | ETHACRYNIC ACID DERIVATIVES AS INHIBITORS OF MPRO PROTEASE AND SARS-COV-2 REPLICATION | UNIVERSITE EURO-MEDITERRANEENNE DE FES (MA) | 2022-11-17 | — | — | WO | disclosed |