Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619809 | 1.00 | MKNK1 (0.43) | MKNK1MKNK2DDB1CRBNHPGD | |
| Hydrochloric Acid SCHEMBL8102714 | 0.98 | MKNK1 (0.42) | MKNK1MKNK2DDB1CRBNHPGD | |
| Hydrochloric Acid SCHEMBL1900003 | 0.98 | MKNK1 (0.42) | MKNK1MKNK2DDB1CRBNHPGD | |
| SCHEMBL27921481 | 0.88 | TRPV1 (0.41) | MKNK1MKNK2DDB1CRBNALDH1A1 | |
| SCHEMBL256207 | 0.78 | CYP11B1 (0.43) | CCR4KDRCYP1A2MEN1KMT2A | |
| SCHEMBL4953525 | 0.78 | MKNK1 (0.44) | MKNK1MKNK2DDB1CRBNHPGD | |
| SCHEMBL6118555 | 0.77 | SLC9A1 (0.40) | MKNK1MKNK2DDB1CRBNHPGD | |
| SCHEMBL19713024 | 0.77 | PDCD1 (0.45) | ALDH1A1MPOKDRLMNACYP1A2 | |
| SCHEMBL1900443 | 0.76 | CCR4 (0.40) | HPGDMPOCCR4KDRLMNA | |
| SCHEMBL1082224 | 0.76 | CCR4 (0.40) | HPGDHSD17B10TSHRTDP1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182788-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |