Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 3/20 | 0.35 |
| ▸ | F13A1 | P00488 | 2/20 | 0.35 |
| ▸ | TGM1 | P22735 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005759 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1NPSR1PABPC1 | |
| SCHEMBL30005662 | 0.90 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1NPSR1PABPC1 | |
| SCHEMBL30006406 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NPSR1RAB9A | |
| Trifluoroacetic Acid SCHEMBL30005566 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1NPSR1PABPC1 | |
| SCHEMBL30006771 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPSR1PABPC1 | |
| SCHEMBL30005563 | 0.84 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPSR1RAB9A | |
| Trifluoroacetic Acid SCHEMBL30005714 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL30005509 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NPSR1RAB9A | |
| SCHEMBL30006470 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPSR1PABPC1 | |
| SCHEMBL30005289 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1NPSR1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |