Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.55 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.55 |
| ▸ | VSIR | Q9H7M9 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 8/20 | 0.41 |
| ▸ | CTSD | P07339 | 3/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397418 | 0.90 | CD274 (0.42) | CD274PDCD1LG2VSIRSIRT2SIRT5 | |
| SCHEMBL30974352 | 0.90 | CD274 (0.57) | CD274PDCD1LG2VSIRBACE1CTSD | |
| SCHEMBL30010859 | 0.87 | CD274 (0.47) | CD274PDCD1LG2VSIRPDCD1 | |
| SCHEMBL30498646 | 0.86 | PDCD1LG2 (0.49) | CD274PDCD1LG2VSIRECE1 | |
| SCHEMBL30851137 | 0.85 | SIRT2 (0.37) | CD274PDCD1LG2BACE1CTSDSIRT2 | |
| SCHEMBL30340139 | 0.85 | PDCD1LG2 (0.51) | CD274PDCD1LG2VSIRBACE1ECE1 | |
| SCHEMBL29697180 | 0.83 | PDCD1LG2 (0.50) | CD274PDCD1LG2VSIRBACE1CTSD | |
| SCHEMBL30712169 | 0.83 | BACE1 (0.47) | CD274PDCD1LG2BACE1CTSDECE1 | |
| SCHEMBL29434587 | 0.83 | ECE1 (0.52) | CD274PDCD1LG2BACE1CTSDECE1 | |
| SCHEMBL29630757 | 0.83 | ECE1 (0.52) | CD274PDCD1LG2BACE1CTSDECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076534-A1 | SMART DRUG DELIVERY SYSTEM AND PHARMACEUTICAL KIT FOR DUAL NUCLEAR MEDICAL CYTOTOXIC THERANOSTICS | SCV - SpezialChemikalienVertrieb GmbH (DE) | 2022-10-26 | — | — | EP | claimed |