SCHEMBL29697180

SCHEMBL29697180

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nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDCD1LG2 Q9BQ51 2/20 0.50
CD274 Q9NZQ7 2/20 0.50
ECE1 P42892 3/20 0.47
BACE1 P56817 10/20 0.45
CTSD P07339 4/20 0.45
VSIR Q9H7M9 2/20 0.38
CTSC P53634 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30974352 0.93 CD274 (0.57) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL31121649 0.91 ECE1 (0.49) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL30165201 0.90 ENPEP (0.43) PDCD1LG2CD274BACE1CTSDCTSC
SCHEMBL29630775 0.89 ECE1 (0.54) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29630874 0.89 ECE1 (0.54) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29630884 0.89 ECE1 (0.54) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29630710 0.89 ECE1 (0.54) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29973181 0.88 BACE1 (0.48) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29355062 0.87 ECE1 (0.50) PDCD1LG2CD274ECE1BACE1CTSD
SCHEMBL29658150 0.87 CD274 (0.52) PDCD1LG2CD274ECE1BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861268-B Cell penetrating peptides and methods of making and using the same 恩特拉达治疗学股份有限公司 2025-04-01 CN disclosed
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 PDCD1LG2 1212/4885CD274 1640/4885ECE1 1368/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 PDCD1LG2 1212/4885CD274 1640/4885ECE1 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.