Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TGM2 | P21980 | 10/20 | 0.52 |
| ▸ | F13A1 | P00488 | 5/20 | 0.52 |
| ▸ | TGM1 | P22735 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TGM6 | O95932 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005671 | 0.90 | ALDH1A1 (0.52) | ALDH1A1TGM2F13A1TGM1MEN1 | |
| SCHEMBL30006759 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| Hydrochloric Acid SCHEMBL30004655 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| Hydrochloric Acid SCHEMBL30005683 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| SCHEMBL30006216 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TGM2F13A1TGM1MEN1 | |
| Hydrochloric Acid SCHEMBL30005749 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| SCHEMBL30005768 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TGM2F13A1TGM1MEN1 | |
| SCHEMBL30005796 | 0.78 | ALDH1A1 (0.84) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL30005901 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ANPSR1HTT | |
| SCHEMBL30005769 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |