Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24342283 | 1.00 | HTT (0.36) | HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27158722 | 0.85 | HTT (0.36) | HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21686844 | 0.80 | GABRP (0.34) | HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29870732 | 0.80 | GABRP (0.34) | HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27094078 | 0.78 | NT5E (0.33) | HTTALDH1A1 | |
| SCHEMBL30754562 | 0.78 | NT5E (0.33) | HTTALDH1A1 | |
| SCHEMBL27093842 | 0.78 | — | — | |
| SCHEMBL30754563 | 0.78 | — | — | |
| SCHEMBL31332420 | 0.77 | CYP1A2 (0.35) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21687035 | 0.77 | CYP1A2 (0.35) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322962-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2024-02-21 | — | — | EP | disclosed |
| CN-117500507-A | Phosphorus derivatives as novel SOS1 inhibitors | 拜耳公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022219035-A1 | PHOSPHORUS DERIVATIVES AS NOVEL SOS1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-20 | — | — | WO | disclosed |