Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753643 | 1.00 | SRC (0.54) | SRCCES1KCNN4TSHRELANE | |
| SCHEMBL27722489 | 0.81 | SRC (0.72) | SRCCES1KCNN4TSHRELANE | |
| SCHEMBL1843233 | 0.81 | CES1 (0.38) | SRCCES1TSHRNPC1MAPK1 | |
| SCHEMBL27700743 | 0.81 | CES1 (0.38) | SRCCES1TSHRMAPK1KMT2A | |
| SCHEMBL1845079 | 0.81 | CES1 (0.38) | SRCCES1TSHRNPC1MAPK1 | |
| SCHEMBL3670563 | 0.78 | SRC (0.68) | SRCCES1KCNN4TSHRELANE | |
| SCHEMBL8071585 | 0.78 | CES1 (0.47) | SRCCES1TSHRMAPK1POLB | |
| SCHEMBL29634553 | 0.72 | CES1 (0.38) | SRCCES1TSHRMAPK1POLB | |
| SCHEMBL1846320 | 0.72 | CES1 (0.38) | SRCCES1TSHRMAPK1POLB | |
| SCHEMBL1846060 | 0.72 | CES1 (0.38) | SRCCES1TSHRMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | JIANGSU VANGUARD PHARMACEUTICAL CO., LTD. (CN) | 2023-07-04 | — | — | US | disclosed |
| US-20220372058-A1 | Substituted Pyrazole Compound, Preparation Method Therefor, Pharmaceutical Composition and Medical Use Thereof | JIANGSU VANGUARD PHARMACEUTICAL CO., LTD (CN) | 2022-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372058-A1 | Substituted Pyrazole Compound, Preparation Method Therefor, Pharmaceutical Composition and Medical Use Thereof | FARS2, GOT2, HADHB | SRC 3419/4885CES1 1638/4885KCNN4 3307/4885 |
| US-11692004-B2 | Substituted pyrazole compound, preparation method therefor, pharmaceutical composition and medical use thereof | FARS2, GOT2, HADHB | SRC 3419/4885CES1 1638/4885KCNN4 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.