GOT2

Aspartate aminotransferase, mitochondrial · P00505 · GOT2 on Sugi Atlas →

0 patent compounds predicted against GOT2, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to GOT2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Antecedent Metabolic Health and Metformin Aging Study PHASE3COMPLETED
Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes PHASE3COMPLETED
A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors PHASE3COMPLETED
The Effect of Combination Ultra Q10 and L-carnitine on the Course of Myelodysplastic Syndrome PHASE2/PHASE3UNKNOWN
Immunotherapy With Racotumomab in Advanced Lung Cancer PHASE3UNKNOWN
Effect of Tulsi (Ocimum Sanctum) on Biochemical Parameters in Young Overweight and Obese Subjects PHASE2COMPLETED
Overcoming Primary Resistance to Immunotherapy in Metastatic Melanoma PHASE2COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic PHASE2ACTIVE_NOT_RECRUITING
Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria PHASE1/PHASE2SUSPENDED
Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans PHASE2RECRUITING
Acetylcarnitine and Insulin Sensitivity PHASE2COMPLETED
An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia PHASE2COMPLETED
Pembrolizumab in Treating Patients With Advanced Merkel Cell Cancer PHASE2COMPLETED
BTK Inhibitor DTRMWXHS-12 in Mantle Cell Lymphoma PHASE1COMPLETED
Assessment of Safety ,Tolerance and Pharmacokinetics Clinical Efficacy With BAT1308 in Advanced Solid Tumors PHASE1COMPLETED
Dose Escalation Study of Continuous Once-daily Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors PHASE1COMPLETED
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations PHASE1NOT_YET_RECRUITING
Predicts Mortality by AST/ALT Ration in Patients with Sepsis and Septic Shock During ICU Admissin nanNOT_YET_RECRUITING
Metabolic Determinants of Cardiac Function nanCOMPLETED
Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN) nanUNKNOWN
Relationship Between Fatigue and Mitochondrial Damage in Patients With HIV/AIDS nanCOMPLETED
Elucidating Hepatic Metabolism in Non-alcoholic Fatty Liver Disease nanENROLLING_BY_INVITATION
Acute Hepatitis in Pediatrics nanRECRUITING
Hepatic Energy Fluxes in NASH and NAS Patients nanACTIVE_NOT_RECRUITING
Liver Function Abnormalities in Patients With Acute Heart Failure nanNOT_YET_RECRUITING
Metabolomic Analysis of Body Fluid of Medulloblastoma in Children nanUNKNOWN
Lifestyle Intervention in Preparation for Pregnancy (LIPP) nanCOMPLETED
Effect of Blueberry Supplementation on Liver Enzymes, Muscle Injury and Respiratory Parameter in Football Athletes: A Eight-Week Training Study nanCOMPLETED
Impact of Body Composition on Bisoprolol and Ramipril Pharmacokinetics in Patients With Chronic Heart Failure nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a GOT2 binder may also engage these)

ProteinNameSimilarity
Q5REB0 1.000 Q5REB0 →
P05202 1.000 P05202 →
P00506 1.000 P00506 →
P00508 1.000 P00508 →
P12345 1.000 P12345 →
P00507 1.000 P00507 →
Q4R559 1.000 Q4R559 →
P12344 1.000 P12344 →
P08907 1.000 P08907 →
Q28F67 1.000 Q28F67 →
Q7SYK7 1.000 Q7SYK7 →
P46643 1.000 P46643 →
Q22067 0.993 Q22067 →
P37833 0.993 P37833 →
P23542 0.993 P23542 →
O94320 0.993 O94320 →
Q55F21 0.993 Q55F21 →
P26563 0.992 P26563 →
P46248 0.991 P46248 →
P28011 0.989 P28011 →
Q54SF7 0.989 Q54SF7 →
P46644 0.989 P46644 →
O42652 0.989 O42652 →
P46645 0.987 P46645 →
P28734 0.986 P28734 →
P46646 0.985 P46646 →
PSAT1 Phosphoserine aminotransferase 0.985 landscape →
Q8R0X7 0.983 Q8R0X7 →
Q52RG7 0.982 Q52RG7 →
Q9V7Y2 0.982 Q9V7Y2 →