Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27267490 | 0.91 | POLB (0.55) | POLBMEN1KMT2AGPR119 | |
| SCHEMBL27092752 | 0.87 | POLB (0.63) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL3064320 | 0.79 | CYP2C19 (0.50) | MEN1KMT2AALDH1A1NPC1MAPT | |
| SCHEMBL30006703 | 0.77 | CCNA2 (0.55) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL20817804 | 0.77 | ALDH1A1 (0.54) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL30476370 | 0.77 | ALDH1A1 (0.54) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL1198309 | 0.77 | CCNA2 (0.55) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL3063074 | 0.76 | RPLP1 (0.38) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10137672 | 0.76 | ALDH1A1 (0.54) | POLBALDH1A1NPC1MAPTMAPK1 | |
| SCHEMBL5663995 | 0.75 | POLB (0.52) | POLBALDH1A1NPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323357-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | Siegfried AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022218811-A1 | PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF | SIEGFRIED AG (CH) | 2022-10-20 | — | — | WO | disclosed |